Publications – Page 2

Critical Care Requirements Under Uncontrolled Transmission of SARS-CoV-2.

Author(s): Martínez-Alés G, Domingo-Relloso A, Arribas JR, Quintana-Díaz M, Hernán MA, COVID@HULP Group.Journal: Am J Public HealthPMID: 33734835 August 2021

To estimate the critical care bed capacity that would be required to admit all critical COVID-19 cases in a setting…

Reperfusion Treatment and Stroke Outcomes in Hospitals With Telestroke Capacity.

Author(s): Wilcock AD, Schwamm LH, Zubizarreta JR, Zachrison KS, Uscher-Pines L, Richard JV, Mehrotra AJournal: JAMA NeurolPMID: 33646272 August 2021

Telestroke is increasingly used in hospital emergency departments, but there has been limited research on its impact on treatment and…

Association of Prediagnostic Blood Metabolomics with Prostate Cancer Defined by ERG or PTEN Molecular Subtypes.

Author(s): Feng X, Zhou CK, Clish CB, Wilson KM, Pernar CH, Dickerman BA, Loda M, Finn SP, Penney KL, Schmidt DR, Heiden MGV, Giovannucci EL, Ebot EM, Mucci LAJournal: Cancer Epidemiol Biomarkers PrevPMID: 33627383 August 2021

The gene fusion and loss are two of the most common somatic molecular alterations in prostate cancer. Here, we investigated…

d-dimer and Death in Critically Ill Patients With Coronavirus Disease 2019.

Author(s): Short SAP, Gupta S, Brenner SK, Hayek SS, Srivastava A, Shaefi S, Singh H, Wu B, Bagchi A, Al-Samkari H, Dy R, Wilkinson K, Zakai NA, Leaf DE, STOP-COVID Investigators.Journal: Crit Care MedPMID: 33591017 August 2021

Hypercoagulability may be a key mechanism for acute organ injury and death in patients with severe coronavirus disease 2019, but…

Development and Validation of a Pediatric Comorbidity Index.

Author(s): Sun JW, Bourgeois FT, Haneuse S, Hernández-Díaz S, Landon JE, Bateman BT, Huybrechts KFJournal: Am J EpidemiolPMID: 33124649 August 2021

Comorbidity scores are widely used to help address confounding bias in nonrandomized studies conducted within health-care databases, but existing scores…

Active Surveillance of the Safety of Medications Used During Pregnancy.

Author(s): Huybrechts KF, Kulldorff M, Hernández-Díaz S, Bateman BT, Zhu Y, Mogun H, Wang SVJournal: Am J EpidemiolPMID: 33423046 August 2021

The scientific community relies on postmarketing approaches to define the risk of using medications in pregnancy because information available at…

Assessing Heterogeneity of Treatment Effects in Observational Studies.

Author(s): Robertson SE, Leith A, Schmid CH, Dahabreh IJJournal: Am J EpidemiolPMID: 33083822 August 2021

Here we describe methods for assessing heterogeneity of treatment effects over prespecified subgroups in observational studies, using outcome-model-based (g-formula), inverse…

Parametric g-formula implementations for causal survival analyses.

Author(s): Wen L, Young JG, Robins JM, Hernán MAJournal: BiometricsPMID: 32588909 August 2021

The g-formula can be used to estimate the survival curve under a sustained treatment strategy. Two available estimators of the…

Comparing Effect Estimates in Randomized Trials and Observational Studies From the Same Population: An Application to Percutaneous Coronary Intervention.

Author(s): Matthews AA, Szummer K, Dahabreh IJ, Lindahl B, Erlinge D, Feychting M, Jernberg T, Berglund A, Hernán MAJournal: J Am Heart AssocPMID: 33998290 August 2021

Background To understand when results from observational studies and randomized trials are comparable, we performed an observational emulation of a…

The safety of asthma medications during pregnancy and lactation: Clinical management and research priorities.

Author(s): Chambers CD, Krishnan JA, Alba L, Albano JD, Bryant AS, Carver M, Cohen LS, Gorodetsky E, Hernández-Díaz S, Honein MA, Jones BL, Murray RK, Namazy JA, Sahin L, Spong CY, Vasisht KP, Watt K, Wurst KE, Yao L, Schatz MJournal: J Allergy Clin ImmunolPMID: 33713765 August 2021

Asthma is one of the most common underlying diseases in women of reproductive age that can lead to potentially serious…